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Mitochondrial biogenesis in the parasitic protozoa |
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Trypanosoma brucei |
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Research group of André Schneider |
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Research Interest | |||||||||||||||||
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How widespread is mitochondrial tRNA import?
The limitations to identify tRNA import by bioinformatic approaches are of practical importance. It has recently been shown that a few cytosolic tRNAs are imported into mitochondria of humans and of the yeast Saccharomyces cerevisiae, even though their mitochondrial genomes encode an apparently complete set of mitochondrial tRNAs. Furthermore, the same studies also suggested that yeast mitochondria might have two distinct pathways for tRNA import. These results show that import of tRNAs is much more widespread than predicted by bioinformatic methods and offer the exciting prospect that mitochondrial tRNA import might be universal. References Rinehart, J., Krett, B., Rubio, M.A., Alfonzo, J.D., and Soll, D. (2005) |
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Designed by Christina Schüpbach | Last modification :
07.06.2013
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